Adjunctive Therapies for Bacterial Keratitis

• Published in: Middle East African journal of ophthalmology Vol. 24; no. 1; pp. 11 - 17
• Main Authors: Dakhil, Turki Abdulaziz Bin, Stone, Donald U, Gritz, David C
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.01.2017; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Anti-Bacterial Agents - therapeutic use; Antibiotics; Bacteria; Bacterial infections; Biological Dressings; Care and treatment; Cryotherapy; Cryotherapy - methods; Dosage and administration; Eye Infections, Bacterial - therapy; Gram-positive bacteria; Hospitals; Humans; Hyperbaric Oxygenation - methods; Iodine; Keratitis; Keratitis - therapy; Ocular Infection Update; Ophthalmology; Oxygen therapy; Patients; Respiratory therapy; Surgical Flaps; Transplants & implants; Ulcers; corneal ulcer; bacterial keratitis; Adjunctive therapy
• ISSN: 0974-9233; 0975-1599; 0975-1599; 0974-9233
• DOI: 10.4103/meajo.MEAJO_264_16

Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy.