Rapid measurement of aortic wave velocity: In vivo evaluation

• Published in: Magnetic resonance in medicine Vol. 46; no. 1; pp. 95 - 102
• Main Authors: Kraft, Kenneth A., Itskovich, Vitalii V., Fei, Ding-Yu
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 01.07.2001; Williams & Wilkins
• Subjects: Adult; aorta; Aorta, Thoracic - anatomy & histology; Aorta, Thoracic - physiology; arterial compliance; Biological and medical sciences; Blood Flow Velocity - physiology; Cardiovascular system; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging - methods; Male; Medical sciences; MR blood velocity; MR wave velocity; phase contrast; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Reproducibility of Results; Time Factors; Human; Evaluation; Volunteer; Paramagnetic contrast agent; Nuclear magnetic resonance imaging; In vivo; Sensitivity; Reproducibility; Measurement technique; Non invasive method; Medical imagery; Circulatory system; Kinetics; Aortic valve
• ISSN: 0740-3194; 1522-2594
• DOI: 10.1002/mrm.1164

A 1D MR sequence has been developed for determining aortic flow wave velocity (WV), a metric of arterial compliance, within a single cardiac cycle. Studies were carried out on the thoracic aortas of 10 normal volunteers. Correlative WV data were also acquired from each subject using a conventional phase‐velocity 2D mapping technique. Aortic WV in this cohort was found to range from 411 to 714 cm/s and was highly correlated (R = 0.95) between the two methods. Peak blood velocity was also measured using both methods and found to agree closely. The reproducibility of WV measurements using the rapid 1D method averaged 7.6%, which is comparable or better than that achieved using existing noninvasive techniques. Magn Reson Med 46:95–102, 2001. © 2001 Wiley‐Liss, Inc.