Challenges experienced with early introduction and sustained consumption of allergenic foods in the Enquiring About Tolerance (EAT) study: A qualitative analysis

• Published in: Journal of allergy and clinical immunology Vol. 144; no. 6; pp. 1615 - 1623
• Main Authors: Voorheis, Paula, Bell, Sadie, Cornelsen, Laura, Quaife, Matthew, Logan, Kirsty, Marrs, Tom, Radulovic, Suzana, Craven, Joanna, Flohr, Carsten, Lack, Gideon, Perkin, Michael R., Young, Louise, Offord, Victoria, DeSousa, Mary, Cullen, Jason, Taylor, Katherine, Tseng, Anna, Raji, Bunmi, Byrom, Sarah, Regis, Gillian, Bigwood, Charlie, Stedman, Charlotte, Tonner, Sharon, Banks, Emily, Kahnum, Yasmin, Babic, Rachel, Stockwell, Ben, Thompson, Erin, Wheatley, Lorna, Patkunam, Devi, Richards, Kerry, Pietraszewicz, Ewa, Stephens, Alick, Sudra, Asha, Turcanu, Victor
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2019; Elsevier Limited; Mosby
• Subjects: adherence; Adult; Age; allergens; Babies; breastfeeding; Breastfeeding & lactation; Caregivers; Desensitization, Immunologic; diet; Enrollments; Families & family life; Female; Follow-Up Studies; Food allergies; Food allergy; Food consumption; Food Hypersensitivity - immunology; Food Hypersensitivity - prevention & control; Humans; infancy; Infant; Infant Food; Male; Nutrition; qualitative; Qualitative analysis; Qualitative research; Questionnaires; randomized controlled trial; Studies; Surveys and Questionnaires; RR; Food allergy; EIG; qualitative; adherence; UK; EAT; infancy; diet; breastfeeding; allergens; randomized controlled trial
• ISSN: 0091-6749; 1097-6825
• DOI: 10.1016/j.jaci.2019.09.004

The early introduction group participants of the Enquiring About Tolerance study were asked to undertake a proscriptive regimen of early introduction and sustained consumption of 6 allergenic foods. It was envisaged that this might be challenging, and early introduction group families were presented with an open-text question to express any problems they were experiencing with the regimen in recurring online questionnaires. We sought to analyze these open-text questionnaire responses with the aim of identifying challenges associated with the introduction and regular consumption of allergenic foods. Three combinations of interim questionnaire responses were selected for analysis, representing the early period (4, 5, and 6 months), middle period (8 and 12 months), and late period (24 and 36 months) of participation in the Enquiring About Tolerance study. Responses were assigned a code to describe their content and subsequently grouped into themes to portray key messages. A thematic content analysis allowed for conversion of qualitative codes into quantitative summaries. Three main challenges to allergenic food consumption were identified. First, some children refused the allergenic food, causing a sense of defeat among caregivers. Second, caregivers were concerned that allergenic foods might be causing a reaction, triggering a need for reassurance. Third, practical problems associated with the regimen compromised caregivers' capacity to persist. Understanding the challenges experienced with allergenic food introduction and sustained consumption is the necessary precursor to developing specific communication and support strategies that could be used by caregivers, practitioners, policymakers, and key stakeholders to address these problems. [Display omitted]