Single drop microextraction—Development, applications and future trends

Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extract...

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Published inJournal of Chromatography A Vol. 1217; no. 16; pp. 2326 - 2336
Main Authors Jeannot, Michael A., Przyjazny, Andrzej, Kokosa, John M.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 16.04.2010
Amsterdam; New York: Elsevier
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Online AccessGet full text
ISSN0021-9673
1873-3778
DOI10.1016/j.chroma.2009.10.089

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Abstract Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.
AbstractList Single drop microextraction (SDME) has emerged over the last 10-15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.
Author Kokosa, John M.
Jeannot, Michael A.
Przyjazny, Andrzej
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  givenname: John M.
  surname: Kokosa
  fullname: Kokosa, John M.
  email: jmkokosa@yahoo.com
  organization: MDRC Consulting/Mott Community College, Flint, MI 48503 USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/19932482$$D View this record in MEDLINE/PubMed
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Thu Jan 02 22:03:31 EST 2025
Tue Jul 01 00:46:20 EDT 2025
Thu Apr 24 22:57:18 EDT 2025
Wed Dec 27 19:13:35 EST 2023
Fri Feb 23 02:17:59 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 16
Keywords Solvent microextraction
Single drop microextraction
Liquid-phase microextraction
Language English
License https://www.elsevier.com/tdm/userlicense/1.0
Copyright 2009 Elsevier B.V. All rights reserved.
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PublicationTitle Journal of Chromatography A
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Snippet Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup...
Single drop microextraction (SDME) has emerged over the last 10-15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup...
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SubjectTerms Chemical Fractionation - instrumentation
Chemical Fractionation - methods
chromatography
Forecasting
headspace analysis
Liquid-phase microextraction
microextraction
Osmolar Concentration
Single drop microextraction
Solvent microextraction
solvents
Solvents - chemistry
Temperature
Title Single drop microextraction—Development, applications and future trends
URI https://dx.doi.org/10.1016/j.chroma.2009.10.089
https://www.ncbi.nlm.nih.gov/pubmed/19932482
https://www.proquest.com/docview/742685323
Volume 1217
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