Single drop microextraction—Development, applications and future trends

Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extract...

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Published inJournal of Chromatography A Vol. 1217; no. 16; pp. 2326 - 2336
Main Authors Jeannot, Michael A., Przyjazny, Andrzej, Kokosa, John M.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 16.04.2010
Amsterdam; New York: Elsevier
Subjects
Chemical Fractionation - instrumentation
Chemical Fractionation - methods
chromatography
Forecasting
headspace analysis
Liquid-phase microextraction
microextraction
Osmolar Concentration
Single drop microextraction
Solvent microextraction
solvents
Solvents - chemistry
Temperature
Solvent microextraction
Single drop microextraction
Liquid-phase microextraction
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ISSN0021-9673
1873-3778
DOI10.1016/j.chroma.2009.10.089

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Summary:Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.
Bibliography:http://dx.doi.org/10.1016/j.chroma.2009.10.089
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ISSN:0021-9673
1873-3778
DOI:10.1016/j.chroma.2009.10.089