Chiral silica-based monoliths in chromatography and capillary electrochromatography

Chiral-modified silica-based monoliths have become well-established stationary phases for both high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The silica-based monoliths were fabricated either in situ in the capillaries for nano-HPLC and CEC or in a mould for...

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Bibliographic Details
Published inJournal of Chromatography A Vol. 1217; no. 7; pp. 941 - 952
Main Author Wistuba, Dorothee
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 12.02.2010
Amsterdam; New York: Elsevier
Subjects
Capillary Electrochromatography - methods
CEC
Chiral
Chromatography
Chromatography, High Pressure Liquid - methods
Cyclodextrins - chemistry
Enantiomeric separation
Enantioselectivity
Monolith
Proteins - chemistry
Silicon Dioxide - chemistry
Stereoisomerism
CEC
Enantiomeric separation
Enantioselectivity
Monolith
Chiral
Chromatography
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Summary:Chiral-modified silica-based monoliths have become well-established stationary phases for both high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The silica-based monoliths were fabricated either in situ in the capillaries for nano-HPLC and CEC or in a mould for “conventional” HPLC. The present review summarizes the chiral modification of silica monoliths and the recent development in the field of enantioselective separations by nano-HPLC and CEC.
Bibliography:http://dx.doi.org/10.1016/j.chroma.2009.11.079
ObjectType-Article-2
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0021-9673
1873-3778
DOI:10.1016/j.chroma.2009.11.079