Influence of comorbidities on CD4+/CD8+ proportion in HIV-positive patients in Blumenau, State of Santa Catarina: a retrospective study

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 50; no. 5; pp. 666 - 669
• Main Authors: Batista, Keila Zaniboni Siqueira, Bogoni, Bárbara, Müller, Renata Cristina, Penedo, Camila Corrêa, Hercílio Higino, Filho, da Silva
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Medicina Tropical 01.09.2017; Sociedade Brasileira de Medicina Tropical - SBMT; Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome - blood; Acquired Immunodeficiency Syndrome - epidemiology; Adult; AIDS; Alcoholism; Alcoholism - blood; Alcoholism - epidemiology; Brazil - epidemiology; CD4 antigen; CD4+/CD8+ ratio; CD4-CD8 Ratio - statistics & numerical data; CD8 antigen; Comorbidities; Comorbidity; Data processing; Depression - blood; Depression - epidemiology; Disease transmission; Drug abuse; Female; Herpes zoster; Herpes Zoster - blood; Herpes Zoster - epidemiology; HIV; HIV infection; Human immunodeficiency virus; Humans; Immunity; Immunodeficiency; Male; Medical records; Mental depression; Middle Aged; Patients; Prevalence; Reference Values; Retrospective Studies; Risk Factors; Sex Distribution; Sexually transmitted diseases; Smoking; Smoking - blood; Smoking - epidemiology; STD; TROPICAL MEDICINE; Young Adult; Comorbidities; CD4+/CD8+ ratio; HIV infection
• ISSN: 0037-8682; 1678-9849; 1678-9849
• DOI: 10.1590/0037-8682-0523-2016

The objective was to identify comorbidities related to HIV-positive patients in Blumenau, State of Santa Catarina. A retrospective, descriptive observational design study which analyzed data from 424 patients assisted by the sexually transmitted disease/acquired immunodeficiency syndrome (STD/AIDS) Specialized Care Service (SCS). Of 424 medical records analyzed, 388 patients presented CD4+/CD8+ ratios lower than 1. The most prevalent comorbidities were smoking, depression, alcoholism, and herpes zoster infection, in males and females. The most relevant comorbidity in both genders was herpes zoster, an important marker of immunity in patients. The lowest mean was observed among patients with neurotoxoplasmosis.