Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient

Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anapl...

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Published inCase reports in pathology Vol. 2016; pp. 1280201 - 5
Main Authors Celik, Zeliha Esin, Celik, Murat, Sen, Erdem, Cebeci, Hakan, Ata, Ozlem, Yavas, Cagdas
Format Journal Article
LanguageEnglish
Published United States Hindawi Publishing Corporation 01.01.2016
John Wiley & Sons, Inc
Wiley
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Summary:Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.
Bibliography:ObjectType-Article-1
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Academic Editor: Atif A. Ahmed
ISSN:2090-6781
2090-679X
DOI:10.1155/2016/1280201