High and Rapid Increase in Seroprevalence for SARS-CoV-2 in Conakry, Guinea: Results From 3 Successive Cross-Sectional Surveys (ANRS COV16-ARIACOV)

• Published in: Open forum infectious diseases Vol. 9; no. 5; p. ofac152
• Main Authors: Soumah, Abou Aissata, Diallo, Mamadou Saliou Kalifa, Guichet, Emilande, Maman, David, Thaurignac, Guillaume, Keita, Alpha Kabinet, Bouillin, Julie, Diallo, Haby, Pelloquin, Raphael, Ayouba, Ahidjo, Kpamou, Cece, Peeters, Martine, Delaporte, Eric, Etard, Jean-Francois, Toure, Abdoulaye
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.05.2022
• Subjects: Major; COVID-19; seroprevalence; SARS-CoV-2; population-based survey; Guinea
• ISSN: 2328-8957; 2328-8957
• DOI: 10.1093/ofid/ofac152

Abstract We conducted 3 successive seroprevalence surveys, 3 months apart, using multistage cluster sampling to measure the extent and dynamics of the severe acute respiratory syndrome coronavirus 2 epidemic in Conakry, the capital city of Guinea. Seroprevalence increased from 17.3% (95% CI, 12.4%–23.8%) in December 2020 during the first survey (S1) to 28.9% (95% CI, 25.6%–32.4%) in March/April 2021 (S2), then to 42.4% (95% CI, 39.5%–45.3%) in June 2021 (S3). This significant overall trend of increasing seroprevalence (P < .0001) was also significant in every age class, illustrating a sustained transmission within the whole community. These data may contribute to defining cost-effective response strategies.