Cacipacore virus as an emergent mosquito-borne Flavivirus

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 50; no. 4; pp. 539 - 542
• Main Authors: Figueiredo, Mario Luis Garcia de, Amarilla, Alberto Anastacio, Figueiredo, Glauciane Garcia de, Alfonso, Helda Liz, Lippi, Veronica, Maia, Felipe Gonçalves Motta, Morais, Felipe Alves, Costa, Cristóvão Alves da, Henriques, Dyana Alves, Durigon, Edison Luis, Figueiredo, Luiz Tadeu Moraes, Aquino, Victor Hugo
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Medicina Tropical 01.07.2017; Sociedade Brasileira de Medicina Tropical - SBMT; Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Animals; Approximation; Aquatic insects; Base Sequence; Birds; Brazil; Cacipacore vírus; Culicidae; Culicidae - classification; Culicidae - virology; Emerging Flavivirus; Flavivirus; Flavivirus - classification; Flavivirus - genetics; Mosquitoes; Phylogeny; Polymerase Chain Reaction; Reverse transcription; TROPICAL MEDICINE; Viruses; Brazil; Amazon Basin; Cacipacore vírus; Mosquitoes; Emerging Flavivirus
• ISSN: 0037-8682; 1678-9849; 1678-9849; 0037-8682
• DOI: 10.1590/0037-8682-0485-2016

Cacipacore virus (CPCV), a possible bird-associated flavivirus, has yet to be detected in mosquitoes. Our purpose is examining CPCV in mosquitoes from the Amazon region of Brazil. Approximately 3,253 Culicidae (grouped into 264 pools) were collected from the Amazon region during 2002-2006 and analyzed using a Flavivirus genus-specific reverse transcription- polymerase chain reaction followed by nested polymerase chain reaction assay and by nucleotide sequencing of amplicons. Nucleotide sequences from five mosquito samples showed high similarity to the those of CPCV originally isolated in the Amazon region. This is the first report of CPCV-infected mosquitoes which has implications on the arbovirus maintenance in nature and transmission to man.