Improved method for purification of toxic peptides produced by cyanobacteria

The improved method consists of ODS-silica gel extraction, and separation on silica gel and HPLC with UV (238 nm) detector. The method has been successfully applied to the isolation of toxic peptides from the Monroe and M-228 strains of Microcystis aeruginosa. This method reduces toxin extraction an...

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Bibliographic Details
Published inToxicon (Oxford) Vol. 26; no. 5; p. 433
Main Authors Harada, K, Suzuki, M, Dahlem, A M, Beasley, V R, Carmichael, W W, Rinehart, Jr, K L
Format Journal Article
LanguageEnglish
Published England 1988
Subjects
Chromatography, Gel
Chromatography, High Pressure Liquid
Chromatography, Thin Layer
Cyanobacteria - metabolism
Mass Spectrometry
Peptides - isolation & purification
Peptides - toxicity
Toxins, Biological - isolation & purification
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Summary:The improved method consists of ODS-silica gel extraction, and separation on silica gel and HPLC with UV (238 nm) detector. The method has been successfully applied to the isolation of toxic peptides from the Monroe and M-228 strains of Microcystis aeruginosa. This method reduces toxin extraction and separation time, and so enables a rapid isolation of peptide toxins from cyanobacteria.
ISSN:0041-0101
1879-3150
DOI:10.1016/0041-0101(88)90182-1