Recent developments in Fourier Domain Mode Locked lasers for optical coherence tomography: Imaging at 1310 nm vs. 1550 nm wavelength

• Published in: Journal of biophotonics Vol. 2; no. 6-7; pp. 357 - 363
• Main Authors: Biedermann, Benjamin R., Wieser, Wolfgang, Eigenwillig, Christoph M., Huber, Robert
• Format: Journal Article
• Language: English
• Published: Berlin WILEY-VCH Verlag 01.07.2009; WILEY‐VCH Verlag
• Subjects: Adhesives; Cucumis sativus; Fingers; Fourier Analysis; Fourier domain mode locking; Humans; Lasers; optical coherence tomography; optical frequency domain imaging; Tomography, Optical Coherence - methods; tunable lasers
• ISSN: 1864-063X; 1864-0648
• DOI: 10.1002/jbio.200910028

We report on recent progress in Fourier domain mode‐locking (FDML) technology. The paper focuses on developments beyond pushing the speed of these laser sources. After an overview of improvements to FDML over the last three years, a brief analysis of OCT imaging using FDML lasers with different wavelengths is presented. For the first time, high speed, high quality FDML imaging at 1550 nm is presented and compared to a system at 1310 nm. The imaging results of human skin for both wavelengths are compared and analyzed. Sample arm optics, power on the sample, heterodyne gain, detection bandwidth, colour cut levels and sample location have been identical to identify the influence of difference in scattering and water absorption. The imaging performance at 1310 nm in human skin is only slightly better and the results suggest that water absorption only marginally affects the penetration depth in human skin at 1550 nm. For several applications this wavelength may be preferred. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)