Microbial Keratitis following Self-Retained Cryopreserved Amniotic Membrane

The aim of this study was to report a severe case of mixed fungal and bacterial microbial keratitis following implantation of a self-retained cryopreserved amniotic membrane, PROKERA® SLIM (Bio-Tissue, Inc) in a patient with history of neurotrophic ulcer secondary to herpetic epithelial keratitis. D...

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Bibliographic Details
Published inCase reports in ophthalmology Vol. 13; no. 3; pp. 724 - 729
Main Authors Fairaq, Rafah, AlBalawi, Eman D., Al-Swailem, Samar A.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 01.09.2022
Karger Publishers
Subjects
Antibiotics
Botulinum toxin
Case Report
Case reports
Consent
Cornea
cryopreserved amniotic membrane
Infections
microbial keratitis
mixed fungal and bacterial keratitis
Ophthalmology
prokera
Ulcers
Cryopreserved amniotic membrane
PROKERA
Microbial keratitis
Mixed fungal and bacterial keratitis
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Summary:The aim of this study was to report a severe case of mixed fungal and bacterial microbial keratitis following implantation of a self-retained cryopreserved amniotic membrane, PROKERA® SLIM (Bio-Tissue, Inc) in a patient with history of neurotrophic ulcer secondary to herpetic epithelial keratitis. Despite maximally tolerated topical and systemic therapy, the patient’s eye continued to deteriorate and eventually required evisceration. PROKERA implantation might be associated with severe recalcitrant microbial keratitis. Caution is urged when considering implantation especially in monocular patients.
ISSN:1663-2699
1663-2699
DOI:10.1159/000525659