Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases

• Published in: Environmental science and pollution research international Vol. 28; no. 19; pp. 24270 - 24278
• Main Authors: Rama, José-Luis Rodríguez, Mallo, Natalia, Biddau, Marco, Fernandes, Francisco, de Miguel, Trinidad, Sheiner, Lilach, Choupina, Altino, Lores, Marta
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2021; Springer Nature B.V
• Subjects: Animal diseases; Animal health; Antimicrobial activity; Antimicrobial agents; Antiparasitic agents; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Bacteria; Biocides; Byproducts; E coli; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental science; Feature extraction; Flavonols; Foodborne diseases; Fungicides; Gallates; Glycosides; Gram-negative bacteria; Grapes; Malaria; Mastitis; Microorganisms; Parasites; Phenolic acids; Phenols; Plasmodium falciparum; Root rot; Salmonella; Streptococcus infections; Vector-borne diseases; Waste and Biomass Management & Valorization; Waste Water Technology; Water Management; Water Pollution Control; Wines; Polyphenols; Grape marc; Anti-parasitic; Antibacterial; Natural extract; Enhancement of winemaking by-products
• ISSN: 0944-1344; 1614-7499
• DOI: 10.1007/s11356-019-07472-1

Natural extracts containing high polyphenolic concentration possess antibacterial, anti-parasitic and fungicidal activities. The present research characterises two extracts based on white grape marc, a winemaking by-product, describing their physicochemical features and antimicrobial capacities. The main components of these extracts are phenolic acids, flavan-3-ols and their gallates and flavonols and their glycosides. As a result of this complex composition, the extracts showed pronounced bioactivities with potential uses in agricultural, pharmaceutical and cosmetic industries. Polyphenol compounds were extracted by using hydro-organic solvent mixtures from the by-product of Albariño white wines (Galicia, NW Spain) production. The in vitro antimicrobial activity of these extracts was evaluated on Gram-positive and Gram-negative bacteria and Apicomplexan and Oomycota parasites. Microbial species investigated are causing agents of several human and animal diseases, such as foodborne illnesses ( Bacillus cereus , Escherichia coli , Salmonella enterica , and Toxoplasma gondii ), skin infections and/or mastitis ( Staphylococcus aureus and Streptococcus uberis ), malaria ( Plasmodium falciparum ) and plant infections as “chestnut ink” or “root rot” ( Phytophthora cinnamomi ). Both extracts showed activity against all the tested species, being nontoxic for the host. So, they could be used for the development of biocides to control a wide range of pathogenic agents and contribute to the enhancement of winemaking industry by-products.