Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder

• Published in: Arquivos de neuro-psiquiatria Vol. 75; no. 2; pp. 92 - 95
• Main Authors: Fragoso, Yara Dadalti, Adoni, Tarso, Brooks, Joseph Bruno Bidin, Gomes, Sidney, Goncalves, Marcus Vinicius Magno, Jovem, Cassio Lemos, Matta, Andre Palma da Cunha, Oliveira, Joao Filipe, Siquinelli, Fabio, Tauil, Carlos Bernardo, Troiani, Guilherme Navarro, Wille, Paulo Roberto
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Academia Brasileira de Neurologia - ABNEURO 01.02.2017; Academia Brasileira de Neurologia (ABNEURO)
• Subjects: Adult; Aged; ataxia; Central Nervous System Diseases - diagnostic imaging; encéfalo; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; NEUROSCIENCES; perda auditiva; PSYCHIATRY; Rare Diseases - diagnostic imaging; siderose; Siderosis - diagnostic imaging; ataxia; siderosis; perda auditiva; siderose; encéfalo; hearing loss; brain
• ISSN: 0004-282X; 1678-4227; 1678-4227; 0004-282X
• DOI: 10.1590/0004-282X20170001

Series of cases collected from Brazilian centers. We studied 13 cases of patients presenting with progressive histories of neurological dysfunction caused by SS-CNS. The most frequent clinical findings in these patients were progressive gait ataxia, hearing loss, hyperreflexia and cognitive dysfunction. The diagnoses of SS-CNS were made seven months to 30 years after the disease onset. SS-CNS is a rare disease that may remain undiagnosed for long periods. Awareness of this condition is essential for the clinician.