Phage abortive infection in lactococci: variations on a theme

Abortive infection (Abi) systems, also called phage exclusion, block phage multiplication and cause premature bacterial cell death upon phage infection. This decreases the number of progeny particles and limits their spread to other cells allowing the bacterial population to survive. Twenty Abi syst...

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Bibliographic Details
Published inCurrent opinion in microbiology Vol. 8; no. 4; pp. 473 - 479
Main Authors Chopin, Marie-Christine, Chopin, Alain, Bidnenko, Elena
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2005
Elsevier
Subjects
Bacterial Proteins - genetics
Bacterial Proteins - metabolism
Bacteriophages - pathogenicity
Bacteriophages - physiology
Escherichia coli
Lactococcus lactis
Lactococcus lactis - virology
Life Sciences
BACTERIOPHAGE
PATHOGENICITY
DAIRY PRODUCT
LACTOCOCCUS LACTIS
ABORTIVE INFECTION SYSTEM
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Summary:Abortive infection (Abi) systems, also called phage exclusion, block phage multiplication and cause premature bacterial cell death upon phage infection. This decreases the number of progeny particles and limits their spread to other cells allowing the bacterial population to survive. Twenty Abi systems have been isolated in Lactococcus lactis, a bacterium used in cheese-making fermentation processes, where phage attacks are of economical importance. Recent insights in their expression and mode of action indicate that, behind diverse phenotypic and molecular effects, lactococcal Abis share common traits with the well-studied Escherichia coli systems Lit and Prr. Abis are widespread in bacteria, and recent analysis indicates that Abis might have additional roles other than conferring phage resistance.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1369-5274
1879-0364
1369-5274
DOI:10.1016/j.mib.2005.06.006