The causal effect of oxidative stress on the risk of glaucoma

• Published in: Heliyon Vol. 10; no. 3; p. e24852
• Main Authors: Shi, Ronghua, Wu, Yaxuan, Chen, He, Zhang, Zicheng, Bao, Siqi, Qu, Jia, Zhou, Meng
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.02.2024; Elsevier
• Subjects: Glaucoma; Mendelian randomization study; Oxidative stress; Glaucoma; Oxidative stress; Mendelian randomization study

Glaucoma is a complex multifactorial disease. Oxidative stress has been implicated in its pathogenesis. However, establishing a causal relationship between oxidative stress and glaucoma is challenging due to confounding and reverse causality. In this study, we performed bidirectional two-sample Mend...