The cytochrome P450 superfamily： Key players in plant development and defense

• Published in: Journal of Integrative Agriculture Vol. 14; no. 9; pp. 1673 - 1686
• Main Author: XU Jun, WANG Xin-yu, GUO Wang-zhen (1State Key Laboratory of Crop Genetics Germplasm Enhancement, Hybrid Cotton RD Engineering Research Center, Ministry of Education/College of Agriculture, Nanjing Agricultural University, Nanjing 210095, P.R.China 2College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, P.R.China)
• Format: Journal Article
• Language: English
• Published: Science Press 01.09.2015; State Key Laboratory of Crop Genetics & Germplasm Enhancement, Hybrid Cotton R&D Engineering Research Center, Ministry of Education/Col ege of Agriculture, Nanjing Agricultural University, Nanjing 210095, P.R.China%Col ege of Life Sciences, Nanjing Agricultural University, Nanjing 210095, P.R.China; KeAi Communications Co., Ltd
• Subjects: abiotic; abiotic stress; and; bacteria; biochemical pathways; biotic; biotic and abiotic stress; classification; cytochrome; cytochrome P-450; cytochrome P450; cytochrome P450 phylogenetic classification plant growth and development biotic and abiotic stress; development; fungi; growth; growth and development; insects; mammals; P450; phylogenetic; phylogenetic classification; phylogeny; plant; plant breeding; plant development; plant growth; plant growth and development; secondary metabolites; stress; biotic and abiotic stress; plant growth and development; cytochrome P450; phylogenetic classiifcation
• ISSN: 2095-3119; 2352-3425
• DOI: 10.1016/S2095-3119(14)60980-1

The cytochrome P450 （CYP） superfamily is the largest enzymatic protein family in plants, and it also widely exists in mammals, fungi, bacteria, insects and so on. Members of this superfamily are involved in multiple metabolic pathways with distinct and complex functions, playing important roles in a vast array of reactions. As a result, numerous secondary metabolites are synthesized that function as growth and developmental signals or protect plants from various biotic and abiotic stresses. Here, we summarize the characterization of CYPs, as well as their phylogenetic classification. We also focus on recent advances in elucidating the roles of CYPs in mediating plant growth and development as well as biotic and abiotic stresses responses, providing insights into their potential utilization in plant breeding.