Genetic structure of Aedes aegypti populations in Chiang Mai (Thailand) and relation with dengue transmission

• Published in: Tropical medicine & international health Vol. 7; no. 10; pp. 865 - 872
• Main Authors: Mousson, Laurence, Vazeille, Marie, Chawprom, Srisucha, Prajakwong, Somsak, Rodhain, François, Failloux, Anna‐Bella
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.10.2002; Blackwell Science; Wiley-Blackwell
• Subjects: Aedes; Aedes - genetics; Aedes - virology; Aedes aegypti; Animals; Arboviroses; Biological and medical sciences; Dengue; Dengue - transmission; Dengue fevers; Dengue Virus; Dengue Virus - pathogenicity; Female; genetic structure; Genetics, Population; Human viral diseases; Infectious diseases; Insect Vectors; Insect Vectors - genetics; Insect Vectors - virology; Isoenzymes; Isoenzymes - genetics; Life Sciences; Medical sciences; Microbiology and Parasitology; Polymorphism, Genetic; Thailand; Tropical medicine; Tropical viral diseases; vector competence; Viral diseases; Virology; Thailand; Asia; Dengue 2; Genetic variability; Dengue; Insecta; Transmission; Population structure; Dengue virus 2; Flavivirus; Epidemiology; Population genetics; Infection; Virus; Gene frequency; Arthropoda; Viral disease; Dengue group virus; Arbovirus disease; Culicidae; Aedes aegypti; Flaviviridae; Invertebrata; Vector; Diptera
• ISSN: 1360-2276; 1365-3156
• DOI: 10.1046/j.1365-3156.2002.00939.x

Summary We analysed the population genetic structure and differentiation regarding vector competence for a dengue virus of 15 Aedes aegypti samples collected from Chiang Mai in northern Thailand. Based on polymorphism of 10 isoenzyme loci, genetic differentiation was confirmed among samples collected in different subdistricts (high FST values and P < 0.05). Based on infection rate for a dengue 2 virus, susceptibilities were similar in mosquitoes collected in San Nuea subdistrict and in Choeng Doi subdistrict, and were heterogeneous in populations sampled in other subdistricts. These findings are discussed and related to insecticide treatments.