The status of diabetes control in Asia-a cross-sectional survey of 24 317 patients with diabetes mellitus in 1998

• Published in: Diabetic medicine Vol. 19; no. 12; pp. 978 - 985
• Main Authors: Chuang, L.-M., Tsai, S. T., Huang, B. Y., Tai, T. Y.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.12.2002; Blackwell
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Asia - epidemiology; Asia population; Biological and medical sciences; Blood Glucose - metabolism; Child; Child, Preschool; Cross-Sectional Studies; diabetes management; Diabetes Mellitus - blood; Diabetes Mellitus - epidemiology; Diabetes Mellitus - prevention & control; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; glycaemic control; Glycated Hemoglobin A - analogs & derivatives; Glycated Hemoglobin A - analysis; HbA1c; Humans; Hyperglycemia - blood; Male; Medical sciences; Middle Aged; Residence Characteristics; Tropical medicine; Asia; Endocrinopathy; Human; Kidney disease; Diabetes mellitus; Cardiovascular disease; Exploration; Peripheral neuropathy; 1998; Prevention; Eye disease; Health policy; diabetes management; Hemoglobin A1c; Cross sectional study; Complication; glycaemic control; Diagnosis; Asia population; HbA1c; Comparative study; Glycemia; Public health; Geographical variation
• ISSN: 0742-3071; 1464-5491
• DOI: 10.1046/j.1464-5491.2002.00833.x

Aims To establish the status of diabetes control in Asia, the Diabcare‐Asia 1998 study collected data from 230 diabetes centres in Bangladesh, People's Republic of China, India, Indonesia, Malaysia, Philippines, Singapore, South Korea, Sri Lanka, Taiwan, Thailand and Vietnam from March to December 1998. Methods Data were obtained either by patient interview during the enrolment visit or by reviewing medical records for the most recent laboratory assessment and clinical examinations. Blood samples were also collected during patients’ visits for central assessments of HbA1c (normal range 4.7–6.4%). Results The mean of centrally measured HbA1c was 8.6 ± 2.0% for 18 211 patients (82% of the analysis population). Of the patients with central HbA1c measurements, the majority (55%) had values exceeding 8%, indicative of poor glycaemic control. The prevalence of retinopathy, microalbuminuria and neuropathy was also higher in the group of patients with higher HbA1c. Based on the findings from central HbA1c measurements and reported local HbA1c assessments, it also appears that more patients with poor glycaemic control did not have access to glycated haemoglobin measurements. Mean HbA1c of the diabetic populations in Bangladesh, Indonesia, Korea, Malaysia and Taiwan were significantly lower (all P = 0.0001, except P = 0.0007 for Malaysia), while that of China, India, Philippines and Vietnam was significantly higher (all P = 0.0001) than the grand mean. Conclusions In our study population of the Asian diabetes patients treated at diabetes centres, more than half were not well controlled. The prevalence of diabetic microvascular complications was higher in the group of patients with higher HbA1c. Further therapeutic actions to improve glycaemic control are required to prevent chronic diabetic complications. Diabet. Med. 19, 978–985 (2002)