Clinical Stage I adenocarcinoma of the endometrium—Analysis of recurrences and the potential benefit of staging lymphadenectomy
Two hundred forty-eight consecutive patients with clinical Stage I adenocarcinoma of the endometrium were seen between 8 77 and 8 88 . Twenty-one were medically not operable and eleven others had papillary serous tumors. The remaining 216 were managed by a consistent operative protocol except that r...
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Published in | Gynecologic oncology Vol. 44; no. 1; pp. 17 - 23 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
San Diego, CA
Elsevier Inc
1992
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Two hundred forty-eight consecutive patients with clinical Stage I adenocarcinoma of the endometrium were seen between
8
77
and
8
88
. Twenty-one were medically not operable and eleven others had papillary serous tumors. The remaining 216 were managed by a consistent operative protocol except that routine preoperative cesium was discontinued after
12
83
. Patients received postoperative pelvic radiation on the basis of the depth of invasion, extrauterine pelvic disease, and/or cervix involvement. No patient underwent a pelvic lymphadenectomy. Only palpably suspicious nodes were removed. Twenty-one of these two hundred sixteen patients developed a recurrence. These 21 cases are analyzed for the probability of a staging lymphadenectomy having prevented their recurrence. Median follow-up of all 216 patients is 61 months with a mean time to recurrence of 26.5 months. No patient was lost to follow-up. Patients who recurred are analyzed by grade, depth of invasion, surgical stage, time to recurrence, site of recurrence, survival, protocol breaks, and frozen section discrepancies. No patient recurred on the pelvic sidewall. All patients found to have positive para-aortic nodes have died. No patient who received vaginal and/or pelvic radiation recurred in the pelvis. We conclude that staging lymphadenectomy would not have improved the outcome for these patients. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0090-8258 1095-6859 |
DOI: | 10.1016/0090-8258(92)90005-4 |