Haematological characteristics predicting susceptibility for ascites. 1. High carbon dioxide tensions in juvenile chickens

• Published in: British poultry science Vol. 44; no. 3; pp. 476 - 483
• Main Authors: Scheele, C.W, Klis, J.D. van der, Kwakernaak, C, Buys, N, Decuypere, E
• Format: Journal Article
• Language: English
• Published: England Longman 01.07.2003; Taylor & Francis Group
• Subjects: ambient temperature; Animals; ascites; Ascites - blood; Ascites - epidemiology; Ascites - veterinary; blood; Blood Gas Analysis - veterinary; blood sampling; carbon dioxide; Carbon Dioxide - blood; cardiac-arrhythmias; chickens; Chickens - genetics; Chickens - growth & development; Chickens - metabolism; disturbances; feed conversion; feed intake; Genetic Predisposition to Disease; growing broiler-chickens; growth-rate; heart; heart-failure; Hematocrit - veterinary; Incidence; liver; Male; mitochondrial dysfunction; mortality; Organ Size; physiological variables; Poultry Diseases - blood; Poultry Diseases - epidemiology; Poultry Diseases - physiopathology; poultry housing; pulmonary-hypertension syndrome; Random Allocation; risk; sires; Temperature; thyroid hormones; Thyroid Hormones - blood; Weight Gain
• ISSN: 0007-1668; 1466-1799
• DOI: 10.1080/0007166030001603204

1. Male broilers of two different genetic stocks, a pure broiler sire line (A) and commercially available Ross broilers (B), were used to study the effect of haematological characteristics in juvenile chickens on the development of clinical ascitic signs. Production performance (body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR)) from 448 birds per stock was measured from 2 to 5 weeks of age. Mortality was recorded from 2 to 6 weeks of age. The birds were housed at a low ambient temperature to stimulate the incidence of ascites. 2. From each stock, 32 birds with the highest (high risk: HRc) and 32 birds with the lowest (low risk: LRc) carbon dioxide tensions (pCO2) in venous blood were selected at 11 d of age. These birds were marked for future blood sampling to determine changes in pCO2 with age to relate these values to ascites susceptibility. 3. At 2 weeks of age all birds (including HRc and LRc birds) were allotted to 32 floor pens (one HRc and one LRc in each pen) per stock. Venous blood samples were collected weekly from HRc and LRc birds for blood gas analysis and haematocrit, and at week 5 also for thyroid hormone (T3, T4) concentrations in plasma. At 5 weeks of age all HRc and LRc birds were examined post-mortem, relative heart, lung, and liver weights and arterial pressure index (API) values were recorded. 4. Birds from stock A showed a lower BWG and FCR and notably higher ascites mortality compared with stock B. An effect of pCO2 tensions at d 11 was found on the incidence of ascitic signs in selected birds of both stocks up to week 5. From the HRc groups 30% of the birds showed ascitic signs, whereas this was only 8% in the LRc group. LRc birds of stock B in particular showed constant low API values (20 ± 3%) and none of these birds showed signs of ascites. 5. Our results suggest that the ascites problem in Ross birds can be eliminated by selection for low pCO2 tensions in venous blood. Stock effects on API, liver weight, lung weight, and plasma thyroid hormone independent of pCO2 showed a more complex picture of the ascitic signs in stock A compared with B. 6. We concluded that in this experiment a high pCO2 tension in venous blood measured at d 11 was a reliable predictor for ascites susceptibility observed at 5 weeks of age. A low pCO2 tension provides an appropriate criterion for genetic selection, whereas a high pCO2 tension emphasises the necessity for intensive management in poultry houses.