Application of functionalized nanoparticle for mass spectrometry

• Published in: Journal of nanoscience and nanotechnology Vol. 14; no. 4; p. 3155
• Main Authors: Taira, Shu, Kaneko, Daisaku, Kawamura-Konishi, Yasuko, Ichiyanagi, Yuko
• Format: Journal Article
• Language: English
• Published: United States 01.04.2014
• ISSN: 1533-4880
• DOI: 10.1166/jnn.2014.8473

We synthesized functionalized nanoparticles (NPs) by in mixing aqueous solutions of 3d transition metal (iron, or manganese) chlorides (MCl2 x nH2O) and (3-aminopropyl)triethoxysilane, and in this unique method, monodispersed NPs were obtained in a single step. The prepared NPs examined by X-ray diffraction, transmission electron microscope, Fourier transform infrared spectroscopy and zeta potential measurement. The synthesized NPs surround by amorphous SiO2 and possess amino and hydroxyl groups on NPs surface. The number-average diameter of the NPs was determined to be about 3 and 5 nm. The NPs worked as an ionization assisting reagent in mass spectrometry (MS) by means of what is called nanoparticle assisted laser desorption/ionization (nano-PALDI) MS has begun to be used to analyze low molecular compound. In this paper, we introduced analysis of the food product and pesticide as environmental pollutant by using nano-PALDI MS.