Clonal dissemination of highly virulent extended-spectrum β-lactamase-producing Escherichia coli strains isolated from the urine of non-hospitalised patients in Zagreb region

• Published in: International journal of antimicrobial agents Vol. 31; pp. 19 - 24
• Main Authors: Vranes, Jasmina, Marijan, Tatjana, Bedenic, Branka, Mlinaric-Dzepina, Ana, Katic, Stjepan, Kalenic, Smilja
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2008
• Subjects: Adhesins, Bacterial - analysis; Adolescent; Adult; Aged; Anti-Bacterial Agents - pharmacology; Bacterial Typing Techniques; beta-Lactamases - biosynthesis; Child; Child, Preschool; Clonal dissemination; Cluster Analysis; Community-Acquired Infections - epidemiology; Community-Acquired Infections - microbiology; Community-acquired urinary tract infections; Croatia - epidemiology; DNA Fingerprinting; Electrophoresis, Gel, Pulsed-Field; Escherichia coli - classification; Escherichia coli - drug effects; Escherichia coli - isolation & purification; Escherichia coli Infections - epidemiology; Escherichia coli Infections - microbiology; Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli; Female; Genotype; Hemolysis; Humans; Infant; Infectious Disease; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Serotyping; Urinary Tract Infections - epidemiology; Urinary Tract Infections - microbiology; Urine - microbiology; Croatia; Clonal dissemination; Community-acquired urinary tract infections; Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli
• ISSN: 0924-8579; 1872-7913
• DOI: 10.1016/j.ijantimicag.2007.07.034

Abstract Recent data suggest that extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is an emergent cause of urinary tract infections in non-hospitalised patients in different countries. The aim of this study was to characterise ESBL-producing E. coli strains isolated from the urine of outpatients in the Zagreb region of Croatia. During the 5-month study period, a total of 2451 E. coli strains were isolated from the urine of non-hospitalised patients with significant bacteriuria. A total of 39 ESBL-producing E. coli strains (1.59%) were collected and characterised.