Molecular Mechanisms of Exercise and Healthspan

Healthspan is the period of our life without major debilitating diseases. In the modern world where unhealthy lifestyle choices and chronic diseases taper the healthspan, which lead to an enormous economic burden, finding ways to promote healthspan becomes a pressing goal of the scientific community...

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Bibliographic Details
Published inCells (Basel, Switzerland) Vol. 11; no. 5; p. 872
Main Authors Guan, Yuntian, Yan, Zhen
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 03.03.2022
MDPI
Subjects
adaptations
Aging
Atherosclerosis
Cardiovascular system
Chronic Disease
chronic diseases
Chronic illnesses
Endurance
Exercise
Fitness training programs
Gene expression
Health care
healthspan
Heart failure
Humans
Insulin
Kinases
Life Style
Medicine
Metabolism
Molecular modelling
Mortality
Musculoskeletal system
Physical fitness
Physiology
Quality of life
R&D
Research & development
Review
Risk factors
Weightlifting
United States > US
exercise
healthspan
chronic diseases
adaptations
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Summary:Healthspan is the period of our life without major debilitating diseases. In the modern world where unhealthy lifestyle choices and chronic diseases taper the healthspan, which lead to an enormous economic burden, finding ways to promote healthspan becomes a pressing goal of the scientific community. Exercise, one of humanity's most ancient and effective lifestyle interventions, appears to be at the center of the solution since it can both treat and prevent the occurrence of many chronic diseases. Here, we will review the current evidence and opinions about regular exercise promoting healthspan through enhancing the functionality of our organ systems and preventing diseases.
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ISSN:2073-4409
2073-4409
DOI:10.3390/cells11050872