Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside

The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including acute coronary syndrome, heart failure, diabetes and peripheral vascular disease. The aim of this review was to explore the current literature...

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Published inInternational journal of molecular sciences Vol. 22; no. 23; p. 12874
Main Authors Morrone, Doralisa, Picoi, Maria Elena Lucia, Felice, Francesca, De Martino, Andrea, Scatena, Cristian, Spontoni, Paolo, Naccarato, Antonio Giuseppe, Di Stefano, Rossella, Bortolotti, Uberto, Dal Monte, Massimo, Pini, Stefano, Abelli, Marianna, Balbarini, Alberto
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 28.11.2021
MDPI
Subjects
Acute coronary syndromes
Animals
Bone marrow
Cardiovascular Diseases - physiopathology
Cell Separation
Cells (biology)
Congestive heart failure
Diabetes
Diabetes mellitus
Endothelial Progenitor Cells - physiology
EPC
Flow cytometry
Gene expression
Humans
Ischemia
ischemic heart disease
Medical research
Progenitor cells
Regenerative medicine
Review
Stem cells
Vascular diseases
Vascular endothelial growth factor
ischemic heart disease
EPC
progenitor cells
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Summary:The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including acute coronary syndrome, heart failure, diabetes and peripheral vascular disease. The aim of this review was to explore the current literature focusing on the great opportunity that EPCs can have in terms of regenerative medicine.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms222312874