Prognostic role of pretreatment plasma fibrinogen in patients with solid tumors: A systematic review and meta-analysis

Highlights • The prognostic value of baseline plasma fibrinogen in solid tumors was assessed. • High fibrinogen is associated with poor prognosis of patients with cancer. • High fibrinogen relates to worse survival in non-metastatic and metastatic cancer. • Plasma fibrinogen might be integrated in c...

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Published inCancer treatment reviews Vol. 41; no. 10; pp. 960 - 970
Main Authors Perisanidis, C, Psyrri, A, Cohen, E.E, Engelmann, J, Heinze, G, Perisanidis, B, Stift, A, Filipits, M, Kornek, G, Nkenke, E
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.12.2015
Subjects
Biomarker
Disease Progression
Disease-Free Survival
Fibrinogen - metabolism
Hematology, Oncology and Palliative Medicine
Humans
Meta-analysis
Neoplasms - blood
Neoplasms - mortality
Plasma fibrinogen
Prognosis
Proportional Hazards Models
Solid tumors
Biomarker
Prognosis
Solid tumors
Plasma fibrinogen
Meta-analysis
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Summary:Highlights • The prognostic value of baseline plasma fibrinogen in solid tumors was assessed. • High fibrinogen is associated with poor prognosis of patients with cancer. • High fibrinogen relates to worse survival in non-metastatic and metastatic cancer. • Plasma fibrinogen might be integrated in cancer staging systems. • Plasma fibrinogen could improve treatment decision-making in patients with cancer.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-4
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ISSN:0305-7372
1532-1967
DOI:10.1016/j.ctrv.2015.10.002