Predeposited autologous blood transfusion for surgery in infants and children

• Published in: Journal of pediatric surgery Vol. 30; no. 5; pp. 659 - 661
• Main Authors: Kemmotsu, Hisao, Joe, Kazuya, Nakamura, Hirofumi, Yamashita, Masao
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Philadelphia, PA Elsevier Inc 01.05.1995; Elsevier
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Transfusion, Autologous; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Child; Child, Preschool; Elective Surgical Procedures; Hirschsprung Disease - surgery; Humans; Infant; Medical sciences; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; infant; Autologous blood transfusion; pediatric; Human; Transfusion; Surgery; Samplings; Infant; Autologous system; Preoperative; Child; Blood
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/0022-3468(95)90683-5

Homologous blood transfusions have associated infectious and immunological risks. Since 1989 the authors have conducted predeposited autologous blood transfusions (PABT) for infants and children in whom transfusions were expected to be required during an elective operation. Autologous blood was deposited in 13 patients ranging in age from 9 months to 10 years (median, 21 months) with weight from 7.3 kg to 33.6 kg (median, 10.5 kg). They included eight patients with Hirschsprung's disease, three patients with benign tumors, and two others. The volume of predeposition was calculated to maintain the patients' hematocrit at 30% after collection. Blood was deposited once or twice, 1 to 2 weeks before the operation. The actual volume of predeposited blood was 19.1 ± 2.4 mL/kg in infants with Hirschsprung's disease, and 21.8 ± 10.0 mL/kg in children with Hirschsprung's disease, and 12.6 ± 2.2 mL/kg in children with other diseases. Nine patients were operated on using only PABT, 2 patients required homologous blood transfusions in addition to PABT, and 2 patients did not require any blood transfusions. No complications occurred as a result of PABT except preoperative anemia. PABT is a safe and effective means of procuring blood for intraoperative transfusions in infants and children undergoing major elective general pediatric surgical procedures.