Chronological Endoscopic and Pathological Observations in Russell Body Duodenitis

• Published in: Clinical endoscopy Vol. 49; no. 4; pp. 387 - 390
• Main Authors: Goto, Atsushi, Okamoto, Takeshi, Matsumoto, Masaharu, Saito, Hiroyuki, Yanai, Hideo, Itoh, Hiroshi, Sakaida, Isao
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Gastrointestinal Endoscopy 01.07.2016; Korean Society of Gastrointestinal Endoscopy; 대한소화기내시경학회
• Subjects: Case Report; Duodenal ulcer; Russell body; Russell body duodenitis; 내과학; Russell body; Duodenal ulcer; Russell body duodenitis
• ISSN: 2234-2400; 2234-2443
• DOI: 10.5946/ce.2015.131

A 64-year-old man was found to have a nodule in his right lung. He also complained of nausea and abdominal pain during the clinical course. Esophagogastroduodenoscopy revealed a duodenal ulcer associated with severe stenosis and a suspicion of malignancy. However, three subsequent biopsies revealed no evidence of malignancy. The fourth biopsy showed scattered large eosinophilic cells with an eccentric nucleus, leading to a diagnosis of Russell body duodenitis (RBD). RBD is an extremely rare disease, and little is known about its etiology and clinical course. The pathogenesis of RBD is discussed based on our experience with this case.