The Polymer-Based Technology in the Endovascular Treatment of Abdominal Aortic Aneurysms

An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta that progressively grows until it ruptures. Treatment is typically recommended when the diameter is more than 5 cm. The EVAR (Endovascular aneurysm repair) is a minimally invasive procedure that involves the placement of an ex...

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Published inPolymers Vol. 13; no. 8; p. 1196
Main Authors de Donato, Gianmarco, Pasqui, Edoardo, Panzano, Claudia, Brancaccio, Brenda, Grottola, Gaia, Galzerano, Giuseppe, Benevento, Domenico, Palasciano, Giancarlo
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 07.04.2021
MDPI
Subjects
Aorta
aortic aneurysm
aortic endograft
Biocompatibility
Diameters
endovascular aneurysm repair
FDA approval
Grafting
Health services
O ring seals
Polyethylene glycol
polymer
Polymers
Review
Sealing
Stents
vascular surgery
Veins & arteries
polymer
polyethylene glycol
aortic aneurysm
aortic endograft
vascular surgery
endovascular aneurysm repair
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Summary:An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta that progressively grows until it ruptures. Treatment is typically recommended when the diameter is more than 5 cm. The EVAR (Endovascular aneurysm repair) is a minimally invasive procedure that involves the placement of an expandable stent graft within the aorta to treat aortic disease without operating directly on the aorta. For years, stent grafts' essential design was based on metallic stent frames to support the fabric. More recently, a polymer-based technology has been proposed as an alternative method to seal AAA. This review underlines the two platforms that are based on a polymer technology: (1) the polymer-filled endobags, also known as Endovascular Aneurysm Sealing (EVAS) with Nellix stent graft; and (2) the O-ring EVAR polymer-based proximal neck sealing device, also known as an Ovation stent graft. Polymer characteristics for this particular aim, clinical applications, and durability results are hereby summarized and commented critically. The technique of inflating endobags filled with polymer to exclude the aneurysmal sac was not successful due to the lack of an adequate proximal fixation. The platform that used polymer to create a circumferential sealing of the aneurysmal neck has proven safe and effective.
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ISSN:2073-4360
2073-4360
DOI:10.3390/polym13081196