Nonprocessed adipose tissue graft in the treatment of peri-implant osseous defects in the rabbit's tibiae: a pilot study

• Published in: The Journal of oral implantology Vol. 40; no. 1; pp. 60 - 66
• Main Authors: Zanicotti, Diogo Godoy, Matsubara, Fernanda Brugin, Zielak, João César, Giovanini, Allan Fernando, Urban, Cícero de Andrade, Deliberador, Tatiana Miranda
• Format: Journal Article
• Language: English
• Published: United States Allen Press Inc 01.02.2014
• Subjects: Adipose Tissue - transplantation; Animals; Autografts - transplantation; Blood clots; Body fat; Bone Diseases - pathology; Bone Diseases - surgery; Bone Marrow - pathology; Bone Regeneration - physiology; Bone Transplantation - methods; Collagen; Defects; Dental Implants; Dentistry; Male; Membranes; Membranes, Artificial; Osseointegration - physiology; Osteogenesis - physiology; Pilot Projects; Rabbits; Random Allocation; Skin & tissue grafts; Stem cells; Tibia - pathology; Tibia - surgery; Tissue engineering; Titanium; Transplants & implants; Brazil
• ISSN: 0160-6972; 1548-1336
• DOI: 10.1563/AAID-JOI-D-11-00149

We hypothesized that a new technique using nonprocessed adipose tissue could regenerate bone around dental implants. Eighteen rabbits received 1 implant per tibia surrounded by a surgically created osseous defect. The defects were assigned for treatment into 3 groups: C, AT, and AB. The percentages of bone-to-implant contact were 17.64% ± 16.22% (AB), 3.54% ± 7.08% (AT), and 12.71% ± 10.11% (C) (ρ = 0.25). The use of adipose tissue around surgically created peri-implant osseous defects interferes with bone formation.