Synthesis of Radioiodinated Compounds. Classical Approaches and Achievements of Recent Years

This review demonstrates the progress in the synthesis of radioiodinated compounds over the past decade. The possibilities and limitations of radiopharmaceuticals with different iodine isotopes, as well as the synthesis of low and high molecular weight compounds containing radioiodine, are discussed...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of molecular sciences Vol. 23; no. 22; p. 13789
Main Authors Petrov, Stanislav A., Yusubov, Mekhman S., Beloglazkina, Elena K., Nenajdenko, Valentine G.
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 09.11.2022
MDPI
Subjects
Cancer therapies
Clinical medicine
Drug dosages
Energy
Iodine
Iodine Radioisotopes
Isotopes
Metabolism
Pharmaceuticals
Positrons
Radiation
Radioisotopes
Radiopharmaceuticals
Review
Thyroid cancer
Tomography
synthesis
iodine radioisotopes
radiopharmaceuticals
Online AccessGet full text

Cover

More Information
Summary:This review demonstrates the progress in the synthesis of radioiodinated compounds over the past decade. The possibilities and limitations of radiopharmaceuticals with different iodine isotopes, as well as the synthesis of low and high molecular weight compounds containing radioiodine, are discussed. An analysis of synthesis strategies, substrate frameworks, isolation methods, and metabolic stability, and the possibility of industrial production of radioiodinated organic derivatives which can find applications in the synthesis of drugs and diagnostics are presented.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms232213789