Clear cell variant of pediatric renal cell carcinoma: Rare and challenging

We report a very rare case of clear cell variant of renal cell carcinoma (RCC) in a 3-year-old male child, who presented to us with a left-sided lump in his abdomen. Computed tomography (CT) scan and technetium-99 Dimercapto succinic acid (DMSA) scan revealed a large left renal mass with compromised...

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Bibliographic Details
Published inJournal of cancer research and therapeutics Vol. 19; no. 5; pp. 1443 - 1446
Main Authors Banerjee, Soirindhri, Paul, Souvik, Dastidar, Aloke
Format Journal Article
LanguageEnglish
Published Mumbai Wolters Kluwer India Pvt. Ltd 01.07.2023
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Subjects
Cancer in children
Carcinoma, Renal cell
Care and treatment
Case reports
Children
Diagnosis
Health aspects
Kidney cancer
Metastasis
Pediatric research
Pediatrics
India
Clear cell carcinoma
renal malignancy
translocation
metastatic
pediatric malignancy
pediatric renal cell carcinoma
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Summary:We report a very rare case of clear cell variant of renal cell carcinoma (RCC) in a 3-year-old male child, who presented to us with a left-sided lump in his abdomen. Computed tomography (CT) scan and technetium-99 Dimercapto succinic acid (DMSA) scan revealed a large left renal mass with compromised left renal function. Left-sided nephroureterectomy was done and histopathology demonstrated clear cell carcinoma, possibly translocation-associated RCC (miT family) staged as pT2NxMx. Postoperative CT scans of the thorax and whole abdomen showed secondaries in the lungs and liver. We discussed treatment options in a multidisciplinary tumor board but meanwhile the child succumbed to respiratory failure.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.jcrt_540_21