Textural Analysis of the Hyperdense Artery Sign in Patients with Acute Ischemic Stroke Predicts the Outcome of Thrombectomy

Textural analysis is pivotal in augmenting the diagnosis and outcomes of endovascular procedures for stroke patients. Due to the detection of changes imperceptible to the human eye, this type of analysis can potentially aid in deciding the optimal type of endovascular treatment. We included 40 patie...

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Published inJournal of cardiovascular development and disease Vol. 10; no. 9; p. 359
Main Authors Mărginean, Lucian, Filep, Rares Cristian, Suciu, Bogdan Andrei, Jovin, Tudor G, Ștefan, Paul-Andrei, Lupean, Roxana-Adelina, Arbănași, Eliza Mihaela, Arbănași, Emil Marian, Opriș, Diana Roxana, Timm, Alexander Niklas, Vodă, Rareș, Vunvulea, Vlad
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 24.08.2023
MDPI
Subjects
acute ischemic stroke
aspiration
Blood clots
CT imaging
endovascular
Hospitals
Intervention
Ischemia
large vessel occlusion
Medical imaging
Medical research
Medicine, Experimental
Neuroimaging
Patient outcomes
Patients
Public software
Radiomics
Software
stent-retriever
Stroke
Stroke (Disease)
Stroke patients
thrombectomy
Tomography
Romania
Taiwan
Europe
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Summary:Textural analysis is pivotal in augmenting the diagnosis and outcomes of endovascular procedures for stroke patients. Due to the detection of changes imperceptible to the human eye, this type of analysis can potentially aid in deciding the optimal type of endovascular treatment. We included 40 patients who suffered from acute ischemic stroke caused by large vessel occlusion, and calculated 130 different textural features based on the non-enhanced CT scan using an open-source software (3D Slicer). Using chi-squared and Mann–Whitney tests and receiver operating characteristics analysis, we identified a total of 21 different textural parameters capable of predicting the outcome of thrombectomy (quantified as the mTICI score), with variable sensitivity (50–97.9%) and specificity (64.6–99.4%) rates. In conclusion, CT-based radiomics features are potential factors that can predict the outcome of thrombectomy in patients suffering from acute ischemic stroke, aiding in the decision between aspiration, mechanical, or combined thrombectomy procedure.
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These authors contributed equally to this work.
ISSN:2308-3425
2308-3425
DOI:10.3390/jcdd10090359