Optimal Timing of Image Acquisition for Arterial First Pass CT Myocardial Perfusion Imaging

• Published in: European journal of radiology Vol. 86; pp. 227 - 233
• Main Authors: Pelgrim, G.J, Nieuwenhuis, E, Duguay, T.M, van de Geest, R, Varga-Szemes, A, Slump, C.H, Fuller, S.R, Oudkerk, M, Schoepf, U.J, Vliegenthart, R
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.01.2017
• Subjects: Adenosine; Aged; Contrast Media; Coronary Angiography - methods; Female; Humans; Iodine; Ischemia; Magnetic Resonance Angiography; Male; Middle Aged; Myocardial Ischemia - diagnostic imaging; Myocardial Ischemia - physiopathology; Myocardial perfusion imaging; Myocardial Perfusion Imaging - methods; Myocardial Perfusion Imaging - standards; Radiology; Reference Standards; Retrospective Studies; Tomography; Tomography, X-Ray Computed - methods; X-Ray computed; coronary artery disease; magnetic resonance imaging; myocardial perfusion imaging; MRI; left ventricle; MPI; multiplanar reformat reconstructions; invasive coronary angiography; LV; HU; SPECT; MPR; electrocardiography; CCTA; Computed tomography; Ischemia; Tomography; Iodine; AA; ROIs; Hounsfield unit; AD; coronary computed tomography angiography; X-Ray Computed; ICA; regions of interest; CAD; single photon emission computed tomography; ECG; time-attenuation curves; American Heart Association; CT; descending aorta; TAC; AHA; ascending aorta; Myocardial perfusion imaging; X-Ray computed
• ISSN: 0720-048X; 1872-7727
• DOI: 10.1016/j.ejrad.2016.11.024

Highlights • Optimal timing of static, single-shot CT perfusion scans is important to differentiate ischemic from non-ischemic myocardial segments. • Time delay between reaching 150 and 250 HU thresholds in the ascending aorta and optimal contrast in the myocardium are 4 and 2 s, respectively. • Attenuation difference of more than 15 HU between normal and ischemic myocardium is present during approximately 8 s.