Identification and characterization of a novel orbivirus, Yonaguni orbivirus, isolated from cattle on the westernmost island of Japan

• Published in: Archives of Virology Vol. 165; no. 12; pp. 2903 - 2908
• Main Authors: Murota, Katsunori, Suda, Yuto, Shirafuji, Hiroaki, Ishii, Keiko, Katagiri, Yoshito, Suzuki, Moemi, Kobayashi, Daisuke, Isawa, Haruhiko, Tanaka, Shogo, Yanase, Tohru
• Format: Journal Article
• Language: English
• Published: Vienna Springer Science and Business Media LLC 01.12.2020; Springer Vienna; Springer Nature B.V
• Subjects: Amino acid sequence; Animals; Biomedical and Life Sciences; Biomedicine; blood; Brief Report; Cattle; Culicidae; Genetic relationship; genetic relationships; genome; Genome, Viral; Genomes; Infectious Diseases; Japan; Medical Microbiology; North America; Nucleotide sequence; nucleotides; Open Reading Frames; Orbivirus; Phylogeny; Reoviridae Infections; sequence analysis; Sequence Analysis, DNA; Viral Proteins; Virology; viruses; Japan; North America
• ISSN: 0304-8608; 1432-8798; 1432-8798
• DOI: 10.1007/s00705-020-04803-3

A novel orbivirus (genus Orbivirus , family Reoviridae ), designated Yonaguni orbivirus (YONOV), was isolated from bovine blood collected on a subtropical island of Japan in 2015. The YONOV genome (20,054 nucleotides in total) has a coding arrangement similar to those of mosquito-borne orbiviruses. YONOV has a close genetic relationship to mosquito-borne orbiviruses, especially to Mobuck virus (MBV), which was isolated in North America. However, YONOV and MBV share less than 74% nucleotide sequence identity in the major subcore protein (T2) coding sequence, which satisfies the criterion for species demarcation. It is still uncertain whether YONOV should be assigned to a novel species in the genus Orbivirus .