Carcinoid syndrome and perioperative anesthetic considerations

• Published in: Journal of clinical anesthesia Vol. 23; no. 4; pp. 329 - 341
• Main Authors: Mancuso, Kenneth, MD, Kaye, Alan D., MD, PhD, Boudreaux, J. Philip, MD, FACS, Fox, Charles J., MD, Lang, Patrick, Kalarickal, Philip L., MD, MPH, Gomez, Santiago, MD, Primeaux, Paul J., MD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.06.2011; Elsevier; Elsevier Limited
• Subjects: Anesthesia; Anesthesia & Perioperative Care; Anesthesia - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anesthetics - administration & dosage; Biological and medical sciences; Cancer; Carcinoid syndrome; Cardiovascular disease; Colon; Humans; Malignant Carcinoid Syndrome - diagnosis; Malignant Carcinoid Syndrome - physiopathology; Malignant Carcinoid Syndrome - surgery; Medical sciences; Octreotide; Pain Medicine; Peptides; Perioperative Care - methods; Quality of life; Serotonin; Surgery; Tumors; New York; Serotonin; Octreotide; Carcinoid syndrome; Endocrinopathy; Anesthetic; Analog; Peptide hormone; Neurotransmitter; Anesthesia; Paraneoplastic syndrome; Somatostatin
• ISSN: 0952-8180; 1873-4529
• DOI: 10.1016/j.jclinane.2010.12.009

Abstract Carcinoid tumors are uncommon, slow-growing neoplasms. These tumors are capable of secreting numerous bioactive substances, which results in significant potential challenges in the management of patients afflicted with carcinoid syndrome. Over the past two decades, both surgical and medical therapeutic options have broadened, resulting in improved outcomes. The pathophysiology, clinical signs and symptoms, diagnosis, treatment options, and perioperative management, including anesthetic considerations, of carcinoid syndrome are presented.