Hepatic resections for primary and metastatic tumors using the ultrasonic surgical dissector

• Published in: The American journal of surgery Vol. 163; no. 2; pp. 246 - 250
• Main Authors: Hodgson, W.John B., Morgan, Jean, Byrne, Daniel, DelGuercio, Louis R.M.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.1992; Elsevier; Elsevier Limited
• Subjects: Adolescent; Adult; Aged; Biological and medical sciences; Blood Loss, Surgical; Blood transfusion; Child; Child, Preschool; Colorectal carcinoma; Fatalities; Female; Hepatectomy; Humans; Infant; Liver; Liver Neoplasms - mortality; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Liver, biliary tract, pancreas, portal circulation, spleen; Male; Medical sciences; Metastases; Metastasis; Middle Aged; Postoperative Complications; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Surgical Equipment; Survival; Survival Rate; Tumors; Ultrasonic Therapy - instrumentation; Human; Treatment; Surgery; Liver; Digestive diseases; Hepatic disease; Surgical resection; Metastasis; Technique; Malignant tumor; Ultrasound
• ISSN: 0002-9610; 1879-1883
• DOI: 10.1016/0002-9610(92)90110-D

We have previously described the development of new hepatic surgical techniques using the ultrasonic surgical dissector. With 10 years' experience, we have found that major liver resections have been simplified and that the technique is repeatable in hands other than our own. Thirty-three patients had 37 tumors, averaging 5.65 cm in size, resected with an average blood loss of only 1,020 mL per case, which included 5 right trisegmentectomies, 12 lobectomies, 15 segmental resections, and 4 subsegmental resections. Twenty-two patients had metastatic colorectal cancer. Blood transfusion requirements averaged only 2.24 units in long-term survivors, which was significantly less than the 3.5 units received by patients who have since died (p = 0.092). There were no operative deaths. The median survival of these 22 patients was 56 months, and the 5-year actuarial survival rate was 35%. All of the early deaths occurred in patients with more than four tumors, and no patient with less than four tumors died before 42 months with recurrent disease. Six patients had bilateral tumors, and the fact that patients survived into the fourth and fifth post-resectional year indicates that resection was worth-while. All these patients had Dukes' C primary tumors, but we found no statistical difference in survival between patients with Dukes' B and Dukes' C lesions. The results indicate that hepatic resection with the ultrasonic surgical dissector decreases blood loss, requires few transfusions, is safe to perform, and is associated with excellent long-term survival.