Novel Dynamic Four-Dimensional CT Angiography Revealing 2-Type Motions of Cerebral Arteries

• Published in: Stroke (1970) Vol. 42; no. 3; pp. 815 - 818
• Main Authors: UMEDA, Yasuyuki, ISHIDA, Fujimaro, HAMADA, Kazuhide, FUKAZAWA, Keiji, MIURA, Yoichi, TOMA, Naoki, SUZUKI, Hidenori, MATSUSHIMA, Satoshi, SHIMOSAKA, Shinichi, TAKI, Waro
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.03.2011
• Subjects: Biological and medical sciences; Cerebral Angiography - methods; Cerebral Arteries - diagnostic imaging; Cerebral Arteries - physiopathology; Four-Dimensional Computed Tomography - methods; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Intracranial Aneurysm - diagnosis; Intracranial Aneurysm - diagnostic imaging; Intracranial Aneurysm - physiopathology; Medical sciences; Nervous system (semeiology, syndromes); Neurology; Retrospective Studies; Vascular diseases and vascular malformations of the nervous system; Motion; Stroke; Nervous system diseases; Aneurysm; Cardiovascular disease; Cerebral artery; Cerebral disorder; Vascular disease; Central nervous system disease; CT angiography; Hemodynamics; Angiocomputed tomography; Cerebrovascular disease
• ISSN: 0039-2499; 1524-4628; 1524-4628
• DOI: 10.1161/strokeaha.110.591008

We developed a novel dynamic 4-dimensional CT angiography to accurately evaluate dynamics in cerebral aneurysm. Dynamic 4-dimensional CT angiography achieved high-resolution 3-dimensional imaging with temporal resolution in a beating heart using dynamic scanning data sets reconstructed with a retrospective simulated R-R interval reconstruction algorithm. Movie artifacts disappeared on dynamic 4-dimensional CT angiography movies of 2 kinds of stationary phantoms (titanium clips and dry bone). In the virtual pulsating aneurysm model, pulsation on the dynamic 4-dimensional CT angiography movie resembled actual movement in terms of pulsation size. In a clinical study, dynamic 4-dimensional CT angiography showed 2-type motions: pulsation and anatomic positional changes of the cerebral artery. This newly developed 4-dimensional visualizing technique may deliver some clues to clarify the pathophysiology of cerebral aneurysms.