The use of collagen-based matrices in the treatment of full-thickness wounds

Highlights • A novel collagen–gelatin fleece and Matriderm® were compared. • Deep dermal wound healing was analyzed planimetrically and histologically. • The novel biomaterial shows accelerated dermal wound repair in a minipig model. • We intend to design a composite biomaterial with this scaffold a...

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Bibliographic Details
Published inBurns Vol. 42; no. 6; pp. 1257 - 1264
Main Authors Petersen, Wiebke, Rahmanian-Schwarz, Afshin, Werner, Jan-Ole, Schiefer, Jennifer, Rothenberger, Jens, Hübner, Gunnar, Schaller, Hans-Eberhard, Held, Manuel
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.09.2016
Subjects
Animals
Collagen - therapeutic use
Critical Care
Dermis - pathology
Elastin - therapeutic use
Epidermis - pathology
Gelatin - therapeutic use
Random Allocation
Swine
Swine, Miniature
Tissue Scaffolds
Wound Healing
Wounds and Injuries - pathology
Wounds and Injuries - therapy
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Summary:Highlights • A novel collagen–gelatin fleece and Matriderm® were compared. • Deep dermal wound healing was analyzed planimetrically and histologically. • The novel biomaterial shows accelerated dermal wound repair in a minipig model. • We intend to design a composite biomaterial with this scaffold as a carrier membrane.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0305-4179
1879-1409
DOI:10.1016/j.burns.2016.03.017