Expression of genes encoding laccase and manganese-dependent peroxidase in the fungus Ceriporiopsis subvermispora is mediated by an ACE1-like copper-fist transcription factor

• Published in: Fungal genetics and biology Vol. 46; no. 1; pp. 104 - 111
• Main Authors: Álvarez, José Miguel, Canessa, Paulo, Mancilla, Rodrigo A., Polanco, Rubén, Santibáñez, Paulina A., Vicuña, Rafael
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2009
• Subjects: ACE; ACE1-like copper-fist transcription factor; Amino Acid Sequence; Basidiomycetes; biodegradation; Ceriporiopsis subvermispora; chemistry; Copper; Copper - pharmacology; copper-fist; Coriolaceae; Coriolaceae - enzymology; DNA, Fungal; DNA, Fungal - metabolism; drug effects; Electrophoretic mobility-shift assays; enzyme activity; enzymology; fungal proteins; fungus physiology; gene expression; Gene Expression Regulation, Fungal; Gene Expression Regulation, Fungal - drug effects; genes; genetic complementation; Genetic Complementation Test; genetics; Laccase; Laccase - genetics; Laccase - metabolism; lignin; Ligninolytic; Manganese peroxidase; metabolism; microbial genetics; Molecular Sequence Data; Multicopper oxidase; peptidyl-dipeptidase A; Peroxidases; Peroxidases - metabolism; Phanerochaete chrysosporium; pharmacology; physiological regulation; Promoter Regions, Genetic; Promoter Regions, Genetic - genetics; Saccharomyces cerevisiae; Saccharomyces cerevisiae - genetics; transcription (genetics); Transcription factor; transcription factors; Transcription Factors - chemistry; Transcription Factors - metabolism; transcriptional activation; white-rot fungi; Multicopper oxidase; Ceriporiopsis subvermispora; ACE; Manganese peroxidase; EMSA; Ligninolytic; MCO; Electrophoretic mobility-shift assays; Transcription factor; Copper; copper-fist; Laccase
• ISSN: 1087-1845; 1096-0937; 1096-0937
• DOI: 10.1016/j.fgb.2008.10.002

The effect of copper on the expression of genes encoding the ligninolytic enzymes laccase ( lcs) and manganese peroxidase ( mnp) in Ceriporiopsis subvermispora was evaluated. This metal increased transcript levels of lcs, mnp1 and mnp2. This finding was not unexpected in the case of lcs, since its p...