Total Synthesis of Terprenin, a Highly Potent and Novel Immunoglobulin E Antibody Suppressant

Regioselective halogenations and Suzuki reactions ensure proper linkage of the aromatic rings in two total syntheses of terprenin (1). Both routes make it possible to prepare 1 efficiently and in large quantity.

Saved in:
Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 37; no. 7; pp. 973 - 975
Main Authors Kawada, Kenji, Arimura, Akinori, Tsuri, Tatsuo, Fuji, Masahiro, Komurasaki, Tadafumi, Yonezawa, Shuji, Kugimiya, Akira, Haga, Nobuhiro, Mitsumori, Susumu, Inagaki, Masanao, Nakatani, Takuji, Tamura, Yoshinori, Takechi, Shozo, Taishi, Teruhiko, Kishino, Junji, Ohtani, Mitsuaki
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag GmbH 20.04.1998
WILEY‐VCH Verlag GmbH
Wiley
Subjects
Chemistry
Chemistry, Multidisciplinary
Cross-coupling
Immunosuppressants
Natural products
Physical Sciences
Science & Technology
Terprenin
Total synthesis
cross-coupling
natural products
total synthesis
terprenin
immunosuppressants
Immunosuppressants
Cross-coupling
Natural products
Total synthesis
Terprenin
Online AccessGet full text

Cover

More Information
Summary:Regioselective halogenations and Suzuki reactions ensure proper linkage of the aromatic rings in two total syntheses of terprenin (1). Both routes make it possible to prepare 1 efficiently and in large quantity.
Bibliography:istex:8F8AA15BF8B2367E7536E9372CC2EEBA8E3A55BC
ark:/67375/WNG-748Z6BDG-7
ArticleID:ANIE973
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(19980420)37:7<973::AID-ANIE973>3.0.CO;2-T