Extended coverage first-pass perfusion imaging using slice-interleaved TSENSE

Parallel imaging applied to first‐pass, contrast‐enhanced cardiac MR can yield greater spatial coverage for a fixed temporal resolution. The method combines rate R = 2 acceleration using TSENSE with shot‐to‐shot interleaving of two slices. The √R SNR loss is largely compensated for by a longer effec...

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Published inMagnetic resonance in medicine Vol. 51; no. 1; pp. 200 - 204
Main Authors Kellman, P., Derbyshire, J.A., Agyeman, K.O., McVeigh, E.R., Arai, A.E.
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2004
Subjects
contrast agent
Contrast Media - administration & dosage
Coronary Circulation
Echo-Planar Imaging - methods
Gadolinium DTPA - administration & dosage
heart
Heart - physiology
Humans
Image Processing, Computer-Assisted
Injections
MRI
perfusion
SENSE
TSENSE
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Summary:Parallel imaging applied to first‐pass, contrast‐enhanced cardiac MR can yield greater spatial coverage for a fixed temporal resolution. The method combines rate R = 2 acceleration using TSENSE with shot‐to‐shot interleaving of two slices. The √R SNR loss is largely compensated for by a longer effective repetition time (TR) and increased flip angle associated with slice interleaving. In this manner, increased spatial coverage is achieved while comparable or better image quality is maintained. Single‐heartbeat temporal resolution was accomplished with spatial coverage of eight slices at heart rates up to 71 bpm, six slices up to 95 bpm, and four slices up to 143 bpm. Experiments in normal subjects (N = 6) were performed to assess signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) values. Magn Reson Med 51:200–204, 2004. Published 2003 Wiley‐Liss, Inc.
Bibliography:ark:/67375/WNG-5WPDQZ32-5
This article is a US Government work and, as such, is in the public domain in the United States of America.
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ArticleID:MRM10663
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Correspondence to: Peter Kellman, Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, 10 Center Drive, MSC-1061, Bldg. 10, Rm. B1D416, Bethesda, MD 20892-1061. E-mail: kellman@nih.gov
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.10663