The significance of infectious disease and microbiota in functional gastrointestinal disorders

The definition of functional gastrointestinal disorders (FGID) used to be disorders that do not manifest into organic abnormalities. However, it was pointed out that chronic GI dysfunctions can develop following bacterial infections such as acute gastroenteritis and viral infections, and some organi...

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Bibliographic Details
Published inJournal of general and family medicine Vol. 18; no. 1; pp. 27 - 31
Main Author Tsuchiya, Kiichiro
Format Journal Article
LanguageEnglish
Published Japan John Wiley & Sons, Inc 01.03.2017
John Wiley and Sons Inc
Subjects
Bacteria
Colon
Immunology
Infections
Infectious diseases
intestinal bacteria
Irritable bowel syndrome
Microbiota
post infectious irritable bowel syndrome
Review
small intestinal bacterial overgrowth
Studies
small intestinal bacterial overgrowth
intestinal bacteria
post infectious irritable bowel syndrome
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Summary:The definition of functional gastrointestinal disorders (FGID) used to be disorders that do not manifest into organic abnormalities. However, it was pointed out that chronic GI dysfunctions can develop following bacterial infections such as acute gastroenteritis and viral infections, and some organic changes in the epithelial cell structure, immunocompetent cells, and inflammatory cytokines were revealed. Recent advancements in analytical methods helped discover changes in the intestinal microbiota of patients with FGID. Correlations between the effects on the enteric environment and clinical conditions and symptoms of FGID are drawing increasing attention.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2189-7948
2189-6577
2189-7948
DOI:10.1002/jgf2.3