Design, Synthesis and Biological Activities of Novel Anthranilic Diamide Insecticide Containing Trifluoroethyl Ether

Two series of novel anthranilic diamide insecticide containing trifluoroethyl ether were designed and synthesized, and their structures were characterized by 1H NMR spectroscopy, elemental analysis and single crystal X-ray diffraction analysis. The insecticidal activities of the new compounds were e...

Full description

Saved in:
Bibliographic Details
Published inChinese journal of chemistry Vol. 30; no. 8; pp. 1748 - 1758
Main Author 赵毓 李永强 熊丽霞 王红学 李正名
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 01.08.2012
WILEY‐VCH Verlag
Wiley
Wiley Subscription Services, Inc
Subjects
anthranilic diamide
Bioassays
Chemistry
Chemistry, Multidisciplinary
insecticidal activity
Insecticides
Physical Sciences
ryanodine receptor
Science & Technology
trifluoroethyl ether
X-ray diffraction
三氟
乙基
二苯乙烯苷
合成
杀虫剂
生物活性
设计
邻氨基
trifluoroethyl ether
N-PYRIDYLPYRAZOLE
POTENT
anthranilic diamide
ryanodine receptor
insecticidal activity
Online AccessGet full text
ISSN1001-604X
1614-7065
DOI10.1002/cjoc.201200362

Cover

More Information
Summary:Two series of novel anthranilic diamide insecticide containing trifluoroethyl ether were designed and synthesized, and their structures were characterized by 1H NMR spectroscopy, elemental analysis and single crystal X-ray diffraction analysis. The insecticidal activities of the new compounds were evaluated. The results of bioassays indicated that some of these title compounds exhibited excellent insecticidal activities. The insecticidal activities of compounds 19a, 19b, 19d, 19g, 19k and 19m against oriental armyworm at 2.5 mg·kg-1 were 100%. The larvicidal activities of 19a, 19b, 19c, 19d, 19e, 19g and 19n against diamond-back moth were 100% at 0.1 mg·kg-1. Surprisingly, most of them still exhibited perfect insecticidal activity against diamond-back moth when the concentration was reduced to 0.05 mg·kg-1, which was higher than the commercialized Chlorantraniliprole.
Bibliography:31-1547/O6
anthranilic diamide, ryanodine receptor, trifluoroethyl ether, insecticidal activity
Two series of novel anthranilic diamide insecticide containing trifluoroethyl ether were designed and synthesized, and their structures were characterized by 1H NMR spectroscopy, elemental analysis and single crystal X-ray diffraction analysis. The insecticidal activities of the new compounds were evaluated. The results of bioassays indicated that some of these title compounds exhibited excellent insecticidal activities. The insecticidal activities of compounds 19a, 19b, 19d, 19g, 19k and 19m against oriental armyworm at 2.5 mg·kg-1 were 100%. The larvicidal activities of 19a, 19b, 19c, 19d, 19e, 19g and 19n against diamond-back moth were 100% at 0.1 mg·kg-1. Surprisingly, most of them still exhibited perfect insecticidal activity against diamond-back moth when the concentration was reduced to 0.05 mg·kg-1, which was higher than the commercialized Chlorantraniliprole.
Zhao Yu, Li Yongqiang, Xiong Lixia, Wang Hongxue,Li Zhengming（National Pesticidal Engineering Centre （ Tianjin）, State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China）
the National Basic Research Program of China - No. 2010CB126106
ark:/67375/WNG-33M0VHMD-K
ArticleID:CJOC201200362
the Specialized Research Fund for the Doctoral Program of Higher Education - No. 20110031120011
the Fundamental Research Funds for the Central Universities
istex:4C57F4B6BFEFCC314C7767D27595F88A429DACD0
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201200362