Use of spirometry‐like measurements to monitor house dust mite‐induced experimental asthma in mice

Weight and age correlated positively with FEV 0.1 and PEF among other lung function parameters in naïve mice. Lung function parameters decline in a model of experimental asthma induced by intranasal HDM administrations. Systemic injections of dexamethasone improved lung function, decreased mast cell...

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Bibliographic Details
Published inAllergy (Copenhagen) Vol. 76; no. 7; pp. 2204 - 2207
Main Authors Alvarado‐Vazquez, Perla A., Mendez‐Enriquez, Erika, Hallgren, Jenny
Format Journal Article
LanguageEnglish
Published Denmark Blackwell Publishing Ltd 01.07.2021
John Wiley and Sons Inc
Subjects
Asthma
house dust mite
Letter to the Editor
Letters to the Editor
lung function
mast cells
mouse model
asthma
lung function
house dust mite
mouse model
mast cells
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Summary:Weight and age correlated positively with FEV 0.1 and PEF among other lung function parameters in naïve mice. Lung function parameters decline in a model of experimental asthma induced by intranasal HDM administrations. Systemic injections of dexamethasone improved lung function, decreased mast cell populations and BAL levels of mast cell protease-1 in the HDM model.
Bibliography:SourceType-Other Sources-1
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Funding informationThis work is supported by grants to JH from the Swedish Research Council, the Swedish Heart‐Lung Foundation, Knut and Alice Wallenberg Foundation, Ruth and Nils‐Erik Stenbäck Foundation, Konsul ThC Bergh's Foundation, and Ellen, Walter and Lennart Hesselman Foundation, to EM‐E from Consejo Nacional de Ciencia y Tecnología (CONACYT) México.
ISSN:0105-4538
1398-9995
1398-9995
DOI:10.1111/all.14681