Phaseolus vulgaris extract affects glycometabolic and appetite control in healthy human subjects

• Published in: British journal of nutrition Vol. 109; no. 10; pp. 1789 - 1795
• Main Authors: Spadafranca, Angela, Rinelli, Samuele, Riva, Antonella, Morazzoni, Paolo, Magni, Paolo, Bertoli, Simona, Battezzati, Alberto
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.05.2013
• Subjects: Adult; Appetite; Appetite Regulation - drug effects; Beans; Biological and medical sciences; blood glucose; Blood Glucose - metabolism; c-peptide; C-Reactive Protein - metabolism; Carbohydrates; Diabetes Mellitus - blood; Diabetes Mellitus - drug therapy; Diet; Dietary Supplements; Double-Blind Method; Feeding. Feeding behavior; Female; food intake; Fundamental and applied biological sciences. Psychology; ghrelin; Ghrelin - blood; glucose; Humans; Insulin; Insulin - blood; Lipids; Male; Metabolism; Metabolism and Metabolic Studies; Obesity - blood; Obesity - drug therapy; Phaseolus; Phaseolus vulgaris; Phytotherapy; placebos; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Postprandial Period; Reference Values; rodents; Satiation - drug effects; satiety; secretion; sensation; Vertebrates: anatomy and physiology, studies on body, several organs or systems; volunteers; Young Adult; Satiety; Glucose metabolism; Phaseolus vulgaris; Mixed meals; Supplements; Appetite; Human; Healthy subject; Nutrition; Meal; Extract; Glucose; Metabolism; Leguminosae; Mixed; Dicotyledones; Angiospermae; Carbohydrate; Spermatophyta

Extracts of Phaseolus vulgaris (beans) are known to reduce glycaemia and food intake in rodents and humans. The present study evaluated the effects of a new, standardised and purified P. vulgaris extract (PVE), when employed as a supplement in a mixed balanced meal (60 % carbohydrates, 25 % lipids a...