Cardiovascular risk after hypertensive disorders of pregnancy in women with and without inheritable Thrombophilia

• Published in: Hypertension in pregnancy Vol. 39; no. 2; pp. 203 - 210
• Main Authors: Schonewille, N. N., Abheiden, C. N. H., Bokslag, A., Thijs, A., De Groot, C. J. M., De Vries, J. I. P., De Boer, M. A.
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.04.2020; Taylor & Francis Group
• Subjects: Adult; Cardiovascular Diseases - etiology; Cardiovascular Diseases - physiopathology; Databases, Factual; Female; Heart Disease Risk Factors; Humans; Hypertension, Pregnancy-Induced - physiopathology; maternal morbidity and mortality; Middle Aged; placenta; Preeclampsia; Pregnancy; Risk Assessment; Thrombophilia - complications; Thrombophilia - physiopathology; maternal morbidity and mortality; placenta; Preeclampsia
• ISSN: 1064-1955; 1525-6065; 1525-6065
• DOI: 10.1080/10641955.2020.1753767

Aim of this study was to compare cardiovascular risk in women with and without inheritable thrombophilia after hypertensive disorders of pregnancy (HDP). Blood pressure, anthropometrics and blood samples were measured 9-13 years after early-onset (<34 weeks) HDP. Amongst the 114 women included, no differences in hypertension (31.1% vs. 33.7%, OR 0.90 95% CI (0.29-2.79)), body mass index > 25 kg/m 2 (43.8% vs. 53.1%, OR 0.69 95% CI (0.24-2.00)) or metabolic syndrome (18.8% vs. 13.3%, OR 1.51 95% CI (0.38-6.02)) were found. These data show similar cardiovascular risk profile in women with and without inheritable thrombophilia.