Poly(lactic acid)/carvacrol-based materials: preparation, physicochemical properties, and antimicrobial activity

The current demand for new antimicrobial systems has stimulated research for the development of poly(lactic acid)/carvacrol (PLA/CAR)-based materials able to hinder the growth and spread of microorganisms. The eco-friendly characteristics of PLA and cytocompatibility make it very promising in the pe...

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Bibliographic Details
Published inApplied microbiology and biotechnology Vol. 104; no. 5; pp. 1823 - 1835
Main Authors Scaffaro, Roberto, Maio, Andrea, Nostro, Antonia
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2020
Springer
Springer Nature B.V
Subjects
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Biocompatibility
Biological properties
Biomedical and Life Sciences
Biomedical materials
Biotechnology
Carvacrol
Drug delivery
Drug delivery systems
Drugs
Food packaging
Green chemistry
Green technology
Life Sciences
Medical devices
Medical electronics
Medical equipment
Microbial Genetics and Genomics
Microbiology
Microorganisms
Mini-Review
Organic chemistry
Physicochemical properties
Polylactic acid
Vehicles
Cabo Verde
Carvacrol
Antimicrobial activity
Drug delivery
PLA
Food and biomedical application
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Summary:The current demand for new antimicrobial systems has stimulated research for the development of poly(lactic acid)/carvacrol (PLA/CAR)-based materials able to hinder the growth and spread of microorganisms. The eco-friendly characteristics of PLA and cytocompatibility make it very promising in the perspective of green chemistry applications as material for food and biomedical employments. The broad-spectrum biological and pharmacological properties of CAR, including antimicrobial activity, make it an interesting bioactive molecule that can be easily compounded with PLA by adopting the same techniques as those commonly used for PLA manufacturing. This review critically discusses the most common methods to incorporate CAR into a PLA matrix and their interference on the morphomechanical properties, release behavior, and antimicrobial activity of systems. The high potential of PLA/CAR materials in terms of chemical-physical and antimicrobial properties can be exploited for the future development of food packaging, coated medical devices, or drug delivery systems.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0175-7598
1432-0614
DOI:10.1007/s00253-019-10337-9