Is physical inactivity and sedentary behavior associated with tumor stage in breast cancer patients? A cross-sectional study of Brazilian women

• Published in: Einstein (São Paulo, Brazil) Vol. 21; p. eAO0215
• Main Authors: Queiroga, Luana de Lima, Pitta, Rafael Mathias, Trevisani, Mayra de França, Montenegro, Carla Giuliano de Sá Pinto, Bugano, Diogo Diniz Gomes, Figueira Junior, Aylton José, Baker, Julien Steven, Bocalini, Danilo Sales, Matos, Luciana Diniz Nagem Janot de
• Format: Journal Article
• Language: English
• Published: Brazil Instituto Israelita de Ensino e Pesquisa Albert Einstein 01.01.2023
• Subjects: Adult; Aged; Brazil; Breast Neoplasms; Cross-Sectional Studies; Exercise; Female; Humans; MEDICINE, GENERAL & INTERNAL; Neoplasm staging; Original; Research Personnel; Sedentary Behavior; Sitting position; Brazil; Sedentary behavior; Breast neoplasms; Exercise; Sitting position; Neoplasm staging
• ISSN: 1679-4508; 2317-6385; 2317-6385
• DOI: 10.31744/einstein_journal/2023AO0215

A comparative analysis of the association between sedentary behavior versus physical activity levels and tumor staging in women with breast cancer. The present research adopted a cross-sectional study design to recruit a total of 55 adult and elderly women newly diagnosed with breast cancer for data collection and analysis. Inclusion criteria involved patients in procession of a formal approval for participation in the study by the treating physician and those not hitherto subjected to the first cycle of chemotherapy. Physical activity levels did not influence the pathological stage of breast cancer (p=0.26) or histological tumor grade (p=0.07) in the analyzed subjects. However, there was a significant association between physical activity levels and responsiveness to hormones (epidermal growth factor receptor (HER2), p<0.05) in the analyzed subjects. Significant difference was detected in the histological tumor grade in relation to the mean time spent sitting during the weekend (p<0.05). However, sedentary behavior had no influence on the tumor stage (p>0.05). Physical activity levels did not influence the tumor stage and histological tumor grade. Sedentary behavior had a significant influence on the histological tumor grade.